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if you are having surgery, including dental surgery, tell your doctor or dentist that you are taking sildenafil. Northwestern’s Hofer arranges for his patients to receive made-to-order pills from a couple of specialty pharmacies.

Check your pills to be sure they’re brand-name VIAGRA—not the generic. If you think your brand-name prescription has been filled with a generic, talk to your pharmacist. Your prescription may have been filled with a generic version instead of brand-name VIAGRA.

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Kamagra jelly is applied for the treatment of erectile dysfunction in men and pulmonary arterial hypertension. “The same patients that have erectile dysfunction often have diabetes or heart disease or other vascular disease,” said Dr Alexander, who is also a practicing primary care physician. The MHRA said that pharmacists will be able to determine whether men can get a 50-mg version of the drug, branded as Viagra Connect. The drug is not intended for patients with severe heart, liver, or kidney conditions, the UK regulators stressed. Pfizer already has employed two separate strategies that may help it hang onto sales in the ED market. It markets Revatio, a lower-dose version of sildenafil intended for pulmonary arterial hypertension.

  • However, in addition to them, you can also encounter such dosages as 75, 200 and even 400 mg.
  • Single oral doses of sildenafil up to 100 mg produced no clinically relevant changes in the ECGs of normal male volunteers.
  • However, prescriptions have dropped more than 20 percent since 2012, as repeated price hikes put the pills out of reach for many men lacking good insurance.
  • There was no impairment of fertility in rats given sildenafil up to 60 mg/kg/day for 36 days to females and 102 days to males, a dose producing an AUC value of more than 25 times the human male AUC.
  • Check your pills to be sure they’re brand-name VIAGRA—not the generic.

Sildenafil acts by blocking phosphodiesterase 5 , an enzyme that promotes breakdown of cGMP, which regulates blood flow in the penis. If you’re holding out for a generic version of branded Viagra, you won’t have to wait much longer. Teva Pharmaceuticals plans to release its generic of the “little blue pill” as early as December. Patients should always ask their doctors for medical advice about adverse events.

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If you’re looking for the same results at a much more affordable price point, consider generic Viagra . Sildenafil citrate is the active chemical ingredient in Viagra that treats erectile dysfunction, which means that the generic med will work exactly the same as its pricier counterpart.

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Sildenafil is in a class of medications called phosphodiesterase inhibitors. Sildenafil treats erectile dysfunction by increasing blood flow to the penis during sexual stimulation. Sildenafil treats PAH by relaxing the blood vessels in the lungs to allow blood to flow easily. In the meantime, some doctors specializing in sexual dysfunction have found other options. Some prescribe generic Revatio, the blood pressure pill Pfizer was testing when older patients reported stronger erections as a side effect.

A 2019 study found that between 3 and 76.5% of men experience erectile dysfunction globally . Sildenafil works by making it easier for blood to flow through your penis. Eating a healthy diet, getting enough physical activity, decreasing stress, practicing relaxation techniques, improving your sleep, and losing weight can often help with ED. Of course, popping a pill can seem easier and quicker than these other approaches but may not be the best longer-term solution and should not be the first option. Pfizer already has seen significant erosion in its sales of Viagra, an iconic blue pill that once topped $2 billion in annual revenue. Pfizer reported Viagra revenue of about $1.6 billion last year.

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The main side effects of Viagra include headache, nasal congestion, dizziness, change in color perception . RxList does not provide medical advice, diagnosis or treatment. Stop taking VIAGRA and call your healthcare provider right away if you have sudden vision loss in one or both eyes. Sexual activity can put an extra strain on your heart, especially if your heart is already weak from a heart attack or heart disease. Ask your doctor if your heart is healthy enough to handle the extra strain of having sex. If you need emergency medical care for a heart problem, it will be important for your healthcare provider to know when you last took VIAGRA.

Medication Categories

There is a potential for cardiac risk of sexual activity in patients with preexisting cardiovascular disease. Co-administration of erythromycin, a moderate CYP3A4 inhibitor, resulted in a 160% and 182% increases in sildenafil Cmax and AUC, respectively. Co-administration of saquinavir, a strong CYP3A4 inhibitor, resulted in 140% and 210% increases in sildenafil Cmax and AUC, respectively. Stronger CYP3A4 inhibitors such as ketoconazole or itraconazole could be expected to have greater effects than seen with saquinavir.